Squalene Market Size & Forecasts 2026-2035, By Segments (End-use, Source), Growth Opportunities, Innovation Landscape, Regulatory Shifts, Strategic Regional Insights (U.S., Japan, China, South Korea, UK, Germany, France), and Competitive Dynamics (Amyris, Sophim, Croda International, Arista Industries, SeaDragon)

Market Outlook

Squalene Market size is forecasted to reach USD 505.53 million by 2035, rising from USD 179.65 million in 2025, at a CAGR of more than 10.9% between 2026 and 2035. In 2026, revenue is projected at USD 197.11 million.

• Base Year Value (2025): USD 179.65 Million
• CAGR (2026-2035): 10.9%
• Forecast Year Value (2035): USD 505.53 Million
• Historical Data Period: 2021-2025
• Largest Region: Asia Pacific
• Forecast Period: 2026-2035

Key Takeaways

• Asia Pacific region captured more than 41.2% revenue share in 2025, spurred by strong cosmetics and pharma demand.
• Asia Pacific region will observe around 12% CAGR during the forecast period, driven by growing personal care and health trends.
• The animal segment reached 54.45% revenue share in 2025, fueled by cost-effective production from shark liver oil.
• With 47.38% market share in 2025, personal care & cosmetics segment’s growth was led by demand for natural ingredients in skincare and anti-aging products.
• The leading players in the squalene market include Amyris (USA), Sophim (France), Croda International (UK), Arista Industries (USA), SeaDragon (New Zealand), Kishimoto Special Liver Oil (Japan), Maruha Nichiro (Japan), Nucelis (USA), Arjuna Natural (India), Ekiz Olive Oil (Turkey).

Market Dynamics

Increasing Demand for Natural Emollients in Cosmetics and Skincare

The squalene market is experiencing significant growth due to the rising consumer preference for natural ingredients in cosmetics and skincare products. As consumers become increasingly aware of the harmful effects of synthetic additives, brands are responding by reformulating their products to include natural emollients like squalene. According to a report by the Personal Care Products Council, the clean beauty movement has prompted major brands to highlight the benefits of natural ingredients, positioning squalene as a key component in moisturizers and serums. This shift not only enhances brand loyalty but also opens avenues for established players to innovate their product lines, while new entrants can capitalize on this trend by offering niche, natural-focused offerings that appeal to eco-conscious consumers.

Rising Use of Squalene in Pharmaceuticals and Nutraceuticals

The squalene market is also being driven by its increasing application in pharmaceuticals and nutraceuticals, where it is recognized for its health benefits, including its role as an immune booster and antioxidant. The World Health Organization has acknowledged squalene's potential in vaccine formulations, especially in adjuvants that enhance the efficacy of vaccines. This growing recognition among healthcare professionals and researchers creates a strategic opportunity for pharmaceutical companies to integrate squalene into their product portfolios. For new entrants, the burgeoning interest in health and wellness products presents a fertile ground for innovation, enabling them to develop squalene-based formulations that cater to health-conscious consumers.

Advances in Plant-Based and Synthetic Squalene Production

Technological advancements in the production of both plant-based and synthetic squalene are reshaping the squalene market, making it more accessible and cost-effective. Innovations in biotechnology, such as fermentation processes utilized by companies like Amyris, have led to the development of sustainable squalene alternatives that do not rely on shark liver oil, addressing ethical concerns and regulatory pressures. This evolution not only aligns with the growing sustainability trends but also presents established players with the chance to enhance their supply chains and reduce costs. Furthermore, new entrants can leverage these advancements to offer differentiated products, positioning themselves as leaders in sustainability within the beauty and health sectors, thus capitalizing on the increasing consumer demand for ethically sourced ingredients.

Growth Driver Assessment Framework
Growth Driver	Impact On CAGR	Regulatory Influence	Geographic Relevance	Adoption Rate	Impact Timeline
Increasing demand for natural emollients in cosmetics and skincare	1.90%	Short term (≤ 2 yrs)	Europe, North America (spillover: Asia Pacific)	Low	Moderate
Rising use of squalene in pharmaceuticals and nutraceuticals	1.60%	Medium term (2–5 yrs)	Asia Pacific, Europe (spillover: North America)	Medium	Moderate
Advances in plant-based and synthetic squalene production	1.50%	Long term (5+ yrs)	North America, Asia Pacific (spillover: Europe)	Low	Slow

Industry Restraints:

Regulatory Compliance Challenges

The squalene market faces significant hurdles due to stringent regulatory compliance requirements, particularly in the cosmetic and pharmaceutical sectors. For instance, the European Union's REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation imposes rigorous testing and registration protocols that can delay product launches and increase operational costs for manufacturers. Companies like Amyris have reported that navigating these complex regulatory landscapes not only strains resources but also creates uncertainty, which can deter investment and innovation. As regulatory bodies increasingly prioritize consumer safety and environmental sustainability, market participants must adapt quickly or risk non-compliance, further complicating the landscape for both established players and new entrants. This ongoing regulatory scrutiny is expected to shape product development strategies and market entry approaches in the near to medium term, as companies weigh the costs of compliance against potential market opportunities.

Supply Chain Disruptions

Another critical restraint impacting the squalene market is the vulnerability of supply chains, particularly in sourcing raw materials. The reliance on shark liver oil and plant-based alternatives creates a precarious situation, as highlighted by the International Union for Conservation of Nature (IUCN), which notes the ecological implications of overfishing and the limited availability of sustainable plant sources. This dependency not only raises ethical concerns but also poses risks of supply shortages, which can lead to price volatility and operational inefficiencies. Established companies like Seppic have begun to explore synthetic alternatives to mitigate these risks, yet the transition involves significant R&D investment and time. As supply chain challenges persist, they are likely to compel market participants to diversify sourcing strategies and invest in sustainability initiatives, shaping competitive dynamics and market structures in the coming years.

Regional Forecast

Asia Pacific Market Statistics:

The Asia Pacific region represented more than 41.2% of the global squalene market in 2025, establishing itself as both the largest and fastest-growing market, with a projected CAGR of 12%. This dominance is largely driven by strong demand from the cosmetics and pharmaceutical sectors, where squalene is increasingly recognized for its moisturizing and anti-aging properties. Consumer preferences are shifting towards natural and sustainable ingredients, prompting manufacturers to innovate and enhance product offerings. Notably, the demand for eco-friendly alternatives is supported by regulatory frameworks in countries like Japan, which emphasize sustainability and safety in consumer products. As a result, the Asia Pacific region presents significant opportunities for investment and growth in the squalene market, driven by evolving consumer behaviors and regulatory support.

Japan is positioned as a pivotal hub in the Asia Pacific squalene market, primarily due to its robust cosmetics industry that prioritizes high-quality, innovative products. The country's strong emphasis on research and development has led to the formulation of advanced squalene-based cosmetics that cater to the discerning preferences of Japanese consumers. For instance, major companies like Shiseido have been integrating squalene into their product lines, recognizing its efficacy and appeal. Additionally, Japan's regulatory environment supports the use of natural ingredients, further fueling market growth. This unique convergence of consumer demand and regulatory support underscores Japan's strategic role in the regional squalene landscape, highlighting its potential to drive innovation and expand market share.

China anchors the Asia Pacific squalene market with its rapidly growing demand for both cosmetics and pharmaceuticals, reflecting a significant cultural shift towards health and wellness. The Chinese market is witnessing an increased inclination towards premium skincare products, with brands like L'Oréal and Amorepacific actively incorporating squalene into their formulations to meet consumer expectations for efficacy and safety. Moreover, the government's focus on enhancing product safety standards has catalyzed a shift towards high-quality, sustainable ingredients, positioning squalene as a preferred choice. This alignment of consumer preferences with regulatory changes not only reinforces China's pivotal role in the squalene market but also amplifies the region's overall growth potential, making it an attractive landscape for investors and strategists.

North America Market Analysis:

North America maintained notable market presence in the squalene market, characterized by moderate growth driven by increasing consumer awareness of natural and sustainable ingredients in personal care and cosmetics. This region is significant due to its robust demand for squalene derived from renewable sources, aligning with the growing trend towards eco-conscious consumerism. Companies are increasingly focusing on transparency in sourcing and production processes, which resonates with a demographic that prioritizes sustainability. Furthermore, advancements in extraction technologies have improved the efficiency and cost-effectiveness of squalene production, enhancing its market viability. The U.S. Food and Drug Administration (FDA) has also been proactive in establishing guidelines for the use of squalene in cosmetics, further solidifying consumer confidence and expanding market opportunities.

The United States plays a pivotal role in the North American squalene market, driven by a strong preference for clean-label products among consumers. The demand for squalene is particularly pronounced in the skincare segment, where brands are capitalizing on the ingredient's moisturizing properties. Regulatory frameworks, such as the Cosmetic Ingredient Review (CIR) program, ensure that squalene products meet safety standards, which bolsters consumer trust and encourages purchasing behavior. Additionally, major cosmetic companies like Estée Lauder and Procter & Gamble have begun to highlight the use of squalene in their formulations, tapping into the growing trend of ingredient transparency. These dynamics position the U.S. as a leader in the North American squalene market, offering substantial opportunities for growth as consumer preferences continue to evolve towards natural and sustainable solutions.

Europe Market Trends:

The squalene market in Europe held a commanding share, driven by a robust demand for natural ingredients in cosmetics and pharmaceuticals. This region's significance stems from its advanced regulatory frameworks and heightened consumer awareness surrounding sustainability, which have fostered a preference for eco-friendly products. The increasing inclination towards clean beauty and health-conscious formulations has catalyzed innovation within the industry, as companies adapt to shifting consumer preferences. For instance, the European Commission's Green Deal emphasizes sustainability, encouraging the use of renewable resources, which aligns with the growing popularity of squalene derived from plant sources. As a result, Europe presents substantial opportunities for investment and growth in the squalene market, particularly as brands prioritize transparency and ethical sourcing in their product offerings.

Germany plays a pivotal role in the European squalene market, characterized by its strong emphasis on innovation and high-quality standards. The country's commitment to sustainability is reflected in its regulatory environment, which supports the development of natural ingredients in personal care products. Companies like BASF have been at the forefront, investing in research to optimize the extraction and application of squalene, thereby enhancing product efficacy. Furthermore, the rising trend of veganism among German consumers has spurred demand for plant-based squalene alternatives, positioning the country as a leader in this segment. This trend underscores the potential for Germany to drive regional growth in the squalene market, aligning with broader European sustainability goals.

France, another key player in the European squalene market, is renowned for its luxury cosmetics sector, which increasingly incorporates squalene for its moisturizing properties. The French market is influenced by a rich cultural heritage that values high-quality, effective beauty products. Brands such as L'Oréal are leveraging advances in biotechnology to source squalene sustainably, appealing to the environmentally conscious consumer. Additionally, the French government’s initiatives to promote organic and natural products further bolster the market, creating a favorable environment for squalene-derived ingredients. As France continues to innovate and prioritize sustainability, it reinforces the region's attractiveness for investment in the squalene market, showcasing significant growth potential.

Regional Market Attractiveness & Strategic Fit Matrix
Parameter	North America	Asia Pacific	Europe	Latin America	MEA
Innovation Hub	Advanced	Developing	Advanced	Developing	Nascent
Cost-Sensitive Region	Medium	High	Medium	High	High
Regulatory Environment	Supportive	Neutral	Restrictive	Neutral	Neutral
Demand Drivers	Moderate	Moderate	Moderate	Weak	Weak
Development Stage	Developed	Developing	Developed	Emerging	Emerging
Adoption Rate	Medium	Medium	Medium	Low	Low
New Entrants / Startups	Moderate	Moderate	Moderate	Sparse	Sparse
Macro Indicators	Strong	Stable	Strong	Weak	Weak

Segmentation Analysis

 

Analysis by Source

The squalene market for the animal segment dominated the segment with a commanding 54.4% share in 2025, primarily due to cost-effective production from shark liver oil. This leadership is driven by the high demand for natural squalene in various applications, particularly in the cosmetics and pharmaceutical industries, where its efficacy and purity are highly valued. The increasing consumer preference for authentic and effective ingredients has led to a notable rise in demand, aligning with sustainability priorities that emphasize ethical sourcing practices. Industry leaders like Amyris have been actively advocating for sustainable alternatives, further enhancing market dynamics. This segment presents strategic advantages for established firms in terms of brand loyalty and for emerging players seeking to innovate in sustainable sourcing. Given the ongoing emphasis on natural ingredients and sustainability, the animal segment is expected to maintain its relevance in the near to medium term as consumers increasingly prioritize ethical considerations in their purchasing decisions.

Analysis by End-use

The squalene market in the personal care & cosmetics segment captured over 47.4% share of the market in 2025, fueled by the escalating demand for natural ingredients in skincare and anti-aging products. This segment's leadership stems from a cultural shift towards clean beauty, where consumers are increasingly scrutinizing ingredient lists and favoring products with natural origins. Major brands, including L'Oréal, have adapted their product lines to incorporate squalene, reflecting changing consumer preferences and technological advancements in formulation. The personal care & cosmetics segment offers strategic opportunities for both established firms and newcomers, allowing them to leverage the growing trend of transparency and sustainability. As the focus on natural beauty continues to gain momentum, this segment is well-positioned to thrive, supported by ongoing innovations in product development and consumer education.

Report Segmentation
Segment	Sub-Segment
End-use	Pharmaceuticals, Personal Care & Cosmetics, Nutraceuticals, Food & Beverages, Others
Source	Animal, Plants, Synthetic

Competitive Landscape

Key players in the squalene market include Amyris, Sophim, Croda International, Arista Industries, SeaDragon, Kishimoto Special Liver Oil, Maruha Nichiro, Nucelis, Arjuna Natural, and Ekiz Olive Oil. These companies are recognized for their strategic positioning and innovation in the squalene sector, with Amyris leading in biotechnological advancements and sustainable sourcing. Sophim and Croda International have established themselves as significant contributors to the cosmetic and pharmaceutical applications of squalene, while Arista Industries and SeaDragon focus on high-quality extraction methods. Japanese firms like Kishimoto Special Liver Oil and Maruha Nichiro leverage their long-standing expertise in marine resources, enhancing their market influence. Nucelis and Arjuna Natural are notable for their commitment to natural and organic products, while Ekiz Olive Oil emphasizes quality through its traditional extraction processes, collectively shaping a diverse and competitive landscape in the squalene market.

The competitive environment in the squalene market is characterized by a series of strategic initiatives that enhance the capabilities and offerings of the leading players. Companies have engaged in various collaborations and partnerships that facilitate innovation and expand their product portfolios, allowing them to cater to the growing demand for sustainable and high-quality squalene. For instance, the emphasis on research and development has led to the introduction of novel extraction techniques and formulations, positioning firms to respond adeptly to evolving consumer preferences. Additionally, some players are exploring synergies through mergers and acquisitions, which not only bolster their market presence but also enhance their technological capabilities. This dynamic interplay among the top companies fosters a competitive edge, driving continuous improvement and adaptation to market trends.

Strategic / Actionable Recommendations for Regional Players

In North America, companies should consider forging alliances with biotechnology firms to harness cutting-edge extraction technologies, thereby elevating their product offerings and addressing sustainability concerns. Engaging in collaborative research initiatives can also position them at the forefront of innovation, helping to capture emerging consumer trends.

In the Asia Pacific region, tapping into local agricultural resources for sustainable sourcing can provide a unique advantage. Building relationships with regional farmers and leveraging traditional practices can enhance product authenticity and appeal, particularly in markets that prioritize natural ingredients.

For players in Europe, focusing on high-growth segments such as clean beauty and wellness products presents significant opportunities. By developing targeted marketing strategies that highlight the benefits of squalene in these areas, companies can effectively differentiate themselves and respond to the competitive landscape.

Competitive Dynamics and Strategic Insights
Assessment Parameter	Assigned Scale	Scale Justification
Innovation Intensity	High	Advances in biofermentation and sustainable production.
Market Concentration	Medium	Mix of large players like Amyris and niche plant-based suppliers.
M&A Activity / Consolidation Trend	Active	Investments in bio-based squalene, e.g., Amyris’s partnerships in 2024.
Degree of Product Differentiation	High	Variations in plant-based vs. animal-derived squalene for cosmetics and pharma.
Competitive Advantage Sustainability	Eroding	Shift to sustainable sources reduces barriers for new biofermentation entrants.
Customer Loyalty / Stickiness	Moderate	Demand for sustainable ingredients drives loyalty, but regulatory shifts cause switching.
Vertical Integration Level	Medium	Some control over biofermentation, but reliance on external raw materials.